Hardware implementation of dynamic radiation therapy verification

The effectiveness of the use of modern technologies and methods of radiation treatment depends on the means of quality control of the operational parameters of the radiotherapy equipment. The development of technical means for verification of the radiation therapy plan, allowing accurate assessment of the three-dimensional dose distribution in the target, is a priority task when introducing innovative methods of radiation treatment. The aim of the work is to develop tools for assessing the three-dimensional dose distribution of radiation therapy plans with intensity modulation using the magnitude of the absolute radiation dose. The authors analyzed the existing technical means and methods for verifying radiation therapy plans on medical linear electron accelerators, and also identified their shortcomings. It is shown that these techniques for verifying the three-dimensional dose distribution do not give an accurate idea of the absolute values of the radiation dose in the target. A system and a method are proposed that allows improving the accuracy of the verification of the radiation therapy plan by using the obtained cross-calibration coefficient determined taking into account the value of the radiation output of the medical linear accelerator immediately at the time of the implementation of both this procedure and the radiation therapy session, as well as a method for verifying the plan radiation therapy with their use.

1. Tarutin I. G., Titovich E. V. Application of Linear Electron Accelerators in High-Tech Radiation Therapy. Minsk, Belaruskaya navuka Publ., 2014. 175 p. (in Russian).

2. Titovich E. V. Tarutin I. G., Gackevich G. V. Verification activities during the irradiation of patients using the IMRT methodology at the N. N. Aleksandrov National Cancer Centre. Ukrainskiy radiologicheskii zhurnal [Ukrainian Radiological Journal], 2014, vol. 22, no. 2. pp. 54–57 (in Russian).

3. Kesen N. D. In Vivo Dosimetry In External Radiotherapy. Turk Onkoloji Dergisi, 2017, vol. 32, no. 4, pp. 173–180. https://doi.org/10.5505/tjo.2017.1667

4. Smirnov V. V. Comparative Сharacteristics of Semiconductor In Vivo Dosimeters. St. Petersburg, 2015. 60 p.

5. Al-Taee A. A., Abdul-Fattah Saleh W., Khalil M. M. In vivo dosimetry evaluation of semiconductor diodes and Thermoluminscence Detectors (TLDS) in advanced radiotherapy techniques. Oncology and Radiotherapy, 2020, vol. 14, no. 4. pp. 31–42.

6. IAEA Human Health Reports No. 8 Development of Procedures for In Vivo Dosimetry in Radiotherapy International Atomic Energy Agency. Available at: https://www-pub.iaea.org/MTCD/Publications/PDF/Pub1606_web.pdf (accessed 1 November 2021).

7. In Vivo Dosimetry System. Available at: https://www.elsesolutions.com/wp-content/uploads/2015/07/In-VivoDosimetry.pdf (accessed 1 November 2021).

8. Van Dam J., Marinello G. Methods for In Vivo Dosimetry in External Radiotherapy. 2nd ed. Brussel, ESTRO, 2006. 79 p.

9. In vivo dosimetry. Available at: https://international.anl.gov/training/materials/AX/Kudchadker/3-Invivo-dosimetry. pdf (accessed 1 November 2021).